Action and mechanism
- It appears to act through modulation of oestrogen receptors, resulting in improvement of climacteric symptoms.
Indications
- MENOPAUSE: Treatment of symptoms related to menopause, such as hot flushes, sweating, sleep disturbances, tiredness, nervousness and mood swings.
Posology
Oral use.
- Adults: 1 tablet/12 h (morning and evening). The first therapeutic results are observed after two weeks of treatment. Since the results obtained are better after prolonged administration, a treatment period of 3 to 6 months is recommended.
Guidelines for correct administration
the tablets should be swallowed without chewing, with some water.
Contraindications
Contraindicated in case of hypersensitivity to Cimicifuga racemosa L. rhizome.
Warnings about excipients:
- This medicinal product contains lactose. Patients with hereditary [LACTOSE INTOLERANCE] or galactose, Lapp's lactase insufficiency or glucose or galactose malabsorption should not take this medicinal product.
Precautions
- Hormone-dependent tumours ([BREAST CANCER], [UTERINE CANCER], [ENDOMETRIAL CANCER]): Lack of studies in women with hormone-dependent tumours discourages its use in this population.
- HEPATITIS], [HEPATIC INSUFFICIENCY]: Patients with a history of hepatic impairment should not take this medicine. Cimicifuga racemosa has been associated with cases of hepatic impairment.
Patient advice:
- Patients should stop treatment and notify a doctor if they notice any of the following symptoms: abnormal tiredness, stomach pain with nausea, brown urine, yellow skin and whites of the eyes (jaundice).
- Patients with a history of liver problems should not take this medicine. If they are already taking it, they should consult their doctor.
- Patients who have had no problems during treatment and have noticed clear signs of improvement may continue with the treatment.
- If during treatment there is a feeling of pressure and swelling in the chest, recurrence of menstruation, as well as in case of persistent and undefined discomfort, the clinical situation should be evaluated.
Adverse reactions
- Occasionally may cause digestive disorders.
- HEPATOTOXICITY: Acute liver damage of varying severity has been reported. Although there has been a temporal relationship between the appearance of these lesions and the intake of this medicinal product, a causal relationship could not be established with certainty.
Overdosage
In case of overdosage, gastrointestinal disturbances may intensify. In this case, treatment should be discontinued and the clinical situation evaluated.
