Mucosan Retard 75 mg 10 Extended-Release Capsules
Action and mechanism
- Mucolytic, expectorant. Ambroxol is N-desmethyl-bromhexine, an active metabolite of bromhexine. Its administration leads to a decrease in the viscosity of bronchial secretions and an increase in their volume, while promoting their expulsion.Its mechanism of action is unknown, but it could be related to an increase in the synthesis of sialomucins through the activation of sialyl transferase, thereby restoring the normal composition of glycoproteins in bronchial mucus secretions and normalising the viscoelasticity of bronchial mucus.It may also stimulate the mucous glands of the bronchial epithelium, increase lysozyme levels, which would break down mucopolysaccharides, and stimulate mucociliary activity.
Indications
- [BRONCHIAL HYPERVISCOSITY].
* Reduction of excessive bronchial viscosity in [COMMON COLD] and [FLU].
Dosage
- Adults, oral: 75 mg/24 h.
- Children and adolescents under 18 years of age, oral: safety and efficacy have not been evaluated.
- Elderly, oral: no dosage adjustment is required. Administration with food: may be taken with or without food. Duration of treatment: consult your doctor if symptoms do not improve after 5 days.
Adverse reactions
Adverse reactions are described according to their frequency, considered very common (>10%), common (1-10%), uncommon (0.1-1%), rare (0.01-0.1%), very rare (<0.01%) or unknown (cannot be estimated from the available data).
- Digestive: common [NAUSEA], [TASTE DISTURBANCES], [HYPOESTHESIA] oral; uncommon [VOMITING], [DIARRHEA], [Dyspepsia], [ABDOMINAL PAIN], [DRY MOUTH]; rare dry throat.
- Dermatological: rare [EXANTEMATIC RASHES], [URTICARIA]; frequency unknown [PRURITUS], [ANGIOEDEMA].
- Allergic: frequency unknown [HYPERSENSITIVITY REACTIONS], [ANAPHYLAXIS].